INFRARED SPECTROSCOPIC INVESTIGATION OF SOME ACETANILIDE DERIVATIVES

determination of olanzapine and thiourea using electrodes modified by dna and film of copper-cobalt hexacyanoferrate & investigation of electro-oxidation of some catechol derivatives in the presence of 4-phenylsemicarbazid

چکیده هدف از این کار بررسی الکترواکسیداسیون کتکول و مشتقات آن در حضور 4-فنیل سمی کاربامازید بوده است اکسیداسیون کتکولها ترکیبات نا پایدار کینونها را تولید می کنند که این ترکیبات می تواند در واکنش مایکل بعنوان پذیرنده نوکلئوفیل عمل نمایند. در ادامه اکسایش کتکولهای (a-c1) را درحضور 4-فنیل سمی کاربامازید در محلول آب/استونیتریل (90/10)بوسیله ولتامتری چرخه ای و کولن متری در پتانسیل ثابت مورد بررسی ...

Binding of Harmine Derivatives to DNA: A Spectroscopic Investigation.

Harmine belongs to a group of β-carboline alkaloids endowed with antitumor properties. Harmine and its derivatives are thought to bind to DNA and interfere with topoisomerase activities. We investigated the base-dependent binding of harmine, and three of its synthetic anticancer-active derivatives to the genomic DNA from calf thymus and two synthetic 20-mer double helices, the poly(dG-dC)·poly(...

Estimation of the Aqueous Solubility of Some Acetanilide Derivatives from Octanol-Water Partition Coefficients and Entropies of Fusion

Some semi empirical equations developed by Yalkowsky et al. were used to estimate the aqueous solubility (SW), of acetaminophen, phenacetin, and acetanilide, using experimental octanol-water partition coefficients (PC), entropies of fusion (∆Sf ), and melting points (tm). The calculated solubilities were compared with those experimentally determined. In almost all cases for acetanilide and phen...

Synthesis and bioactivity of some new [3-[4- methylphenoxymethyl]-4-phenyl-[1,2,4]- triazole-5-thio]acetanilide derivatives

The synthesis of some triazole derivatives starting from 4methyl-phenoloxyacetyl hydrazide is described. In this process, the method for the synthesis of 2-chloroacetanilide had been improved and good yields have been obtained. The chemical structure of all compounds have been elucidated by IR, H NMR, C NMR and elemental analysis studies. All of the compounds have been investigated for plant gr...

Spectroscopic Investigation of Proteins